A sniff that may save the world from Covid.

Exclusive.

In a British National Health Service hospital, fifty British ‘guinea-pigs’ last week sniffed a revolutionary new mixture that fights Covid-19 before it gets into our lungs — using a substance that, by coincidence, is connected with the explosive, nitro-glycerine.

It’s being hailed as a huge potential life-saver: a product that attacks the Covid virus, SAR-CoV-2, while it’s still inside our noses, before it reaches the lungs.  Laboratory tests have shown that this liquid, mainly composed of nitric oxide, kills off ninety-nine-point-nine percent of Covid-causing viruses.  It would be especially vital while most people worldwide have not yet had the vaccine, a company executive told Correspondent.World.

“The SaNOtize nasal spray provides a barrier. It contains nitric oxide which prevents and treats early infection by destroying the virus and impeding viral replication within the cells in the nose. In addition, nitric oxide has been shown to block the ACE-2 receptor essential for the virus to infect our cells. That is what makes our product unique and enables it to stand alone from any other nasal approach,” said Dr Chris Miller, chief science officer and co-founder of SaNOtize.

“It’s a safe technology that could be effective in treating infections, including Covid-19,” Dr Miller said. “Everybody just thinks you get the virus, and it gets into your lungs, and you die, but it’s a progression. First you get exposed to it, and the virus tries to attach to the cells in your nose, and it takes a while to incubate, and multiply in nasal cells for a few days and then the virus will shed into your lungs.”

“What we envision is cleansing the upper respiratory area at various points in the day. In the morning when you get up, where the virus has shed and started collecting in the back of your upper airway, first spray of the day, and then you go out into the day, and you can’t always control social distancing as we end lockdown, and so we have nasal sprays throughout the day.

‘At the end of the day you come home and you basically rinse your nose and your nasopharynx, so that will clean your nose, your sinuses, and the back of your throat where these viruses initially reside,” Dr Miller said.

In addition, nitric oxide has been shown to block the ACE-2 receptor essential for the virus to infect our cells. ‘That is what makes our product unique and enables it to stand alone from any other nasal approach,” said Dr Chris Miller, chief science officer and co-founder of SaNOtize.

“It’s a safe technology that could be effective in treating infections, including Covid-19,” Dr Miller said. “Everybody just thinks you get the virus, and it gets into your lungs, and you die, but it’s a progression. First you get exposed to it, and the virus tries to attach to the cells in your nose, and it takes a while to incubate, and multiply in nasal cells for a few days and then the virus will shed into your lungs.”

“What we envision is cleansing the upper respiratory area at various points in the day. In the morning when you get up, where the virus has shed and started collecting in the back of your upper airway, first spray of the day, and then you go out into the day, and you can’t always control social distancing as we end lockdown, and so we have nasal sprays throughout the day. At the end of the day you come home and you basically rinse your nose and your nasopharynx, so that will clean your nose, your sinuses, and the back of your throat where these viruses initially reside,” Dr Miller said.

Ever since the days of Alfred Nobel, the inventor of dynamite and also the founder of the Nobel Prize, it has been known that nitro-glycerine causes blood vessels to expand.

A Nobel Prize-winner Professor Ferid Murad is working with the SaNOtize team. ‘I believe that they have a safe technology that could be effective in treating infections, including Covid-19,” the professor says.

Explaining its decision to award Professor Murad a Nobel Prize, the Committee making the award wrote:

‘Ferid Murad studied how nitro-glycerine activated an enzyme that formed cyclic guanosine monophosphate (cGMP), which in turn caused blood vessels to expand. In 1976 Murad was able to show that nitro-glycerine produced this effect by emitting nitric oxide (NO),’ the Nobel prize committee stated.

“Nitric oxide is an incredibly versatile molecule that regulates almost everything in our body,” Dr Murad said. “When used therapeutically, it has a well-documented safety profile and is demonstrated to be effective against a wide variety of viruses, bacteria and fungi.

The SaNOtize nasal spray provides a barrier. It contains nitric oxide which prevents and treats early infection by destroying the virus and impeding viral replication within the cells in the nose.

The pharmaceutical online magazine eDrugstore  wrote: ‘The science behind the “little blue pill” may prove to be the hero in the fight against COVID-19.’ 

‘The discovery represented a new principle for transferring signals between cells; a gas as a signal-transferring molecule had never been observed before.’

Dr Miller said he had been an enthusiast for the use of Nitric Oxide for thirty years, but only realised to could effectively fight coronavirus-type infections in twelve years ago.

Purely by coincidence it also has a function associated with erectile problems. The pharmaceutical online magazine eDrugstore  wrote: ‘The science behind the “little blue pill” may prove to be the hero in the fight against COVID-19.’ 

Dr Miller says Nitric Oxide does not itself stimulate erections or other improvements in that sphere. Alas. ‘If it did, I would have been a very rich man by now,’ he laughs.

But if his nasal spray really works, he may also become a multi-millionaire.

The pharmaceutical online magazine eDrugstore  wrote: ‘The science behind the “little blue pill” may prove to be the hero in the fight against COVID-19.’